Mid-America scored the first six points of the game and held the Lady Bison without a basket for the first two minutes. McClure and Reynolds hit back-to-back threes to tie things.
The Lady Bison ended the half on an 8-2 run to take a 28-21 lead at halftime.
OBU led by as many as 18 points in the second half when Reynolds canned a three-pointer for a 64-46 edge with 1:47 to go.
Prince led the Lady Bison with 17 points a dozen rebounds, while Reynolds added 12 points and Charity Fowler 10.
OBU forced 28 turnovers with Ashton Pittman getting six steals and Fowler four.
The Lady Bison defense limited MACU to 31 percent shooting for the game. Parris Price had 16 to lead the Lady Evangels.
Now 15-14 on the season and 11-10 in the SAC, the Lady Bison wrap up the regular season Saturday at top-ranked Oklahoma City.